"Directed & Random Walks in Chemical Space"

• 16:15 - 16:45: Dr. Serhii Zozulia
• 16:45 - 17:15: Dr. Mahmood Nazari

• 16:15 - 16:45: Dr. Enric Herrero
  "Finding Novel Chemotypes in EnamineREAL Using 3D Hydrophobicity Maps"
• 16:45 - 17:15: Dr. Haribubu Arthanari
• 17:15 - 17:45: Dr. Andreas Luttens
  "Exploring chemical space with knowledge-distillation models"

• 16:15 - 16:45: Dr. Anastasia Kolodiazhna
  "Enzymatic synthesis as a method for obtaining optically active compounds"
• 16:45 - 17:15: Dr. Paul Richardson
• 17:15 - 17:45: Prof. Corinna Schindler

"The Cytocapsular Tube a Biomarker of Malignant Cancer and a New Cancer Drug Target"

• 11:00 - 11:30: Dr. Peter Ertl
  "Ring systems in medicinal chemistry - Where the bioactivity is hidden"
• 11:30 - 12:00: Dr. Aleksey Gerasyuto
  "Predict-First" – Where Physics and AI/ML Shape the Future of Drug Discovery"
• 12:00 - 12:30: Dr. Alexander Weber
  "Exploring the Vast Chemical Universe: New Strategies for Identifying Diverse and Tailored Hit Sets"

• 11:00 - 11:30: Dr. Emilia Neuwirt
  "Founder's Insight: Tackling Early Drug Development Challenges with R&D Partners That Deliver"
• 11:30 - 12:00: Prof. Oleksandr Grygorenko
• 12:00 - 12:30: Dr. Anna Vulpetti
  "Integrated Computational and ¹⁹F NMR Screening Approaches Applied to Challenging Targets"

• 11:00 - 11:30: Prof. Valentyn Chebanov
  "Tandem combinations of multicomponent reactions in the synthesis of polypharmacophore organic compounds"
• 12:00 - 12:30: Prof. László Kürti
  "Strain, Weak Bonds, Rearrangement, and Nitrogen Transfer: Harnessing Functionalized Hydroxylamines in Modular Heterocycle Synthesis"

"Rethinking the Funnel – Computational Approaches for Multi-Criteria Screening of Chemical Fragment Spaces"

"Catalyzing Organic Synthesis at Strong Bonds"

• 16:00 - 16:30: Prof. Serhiy Ryabukhin
• 16:30 - 17:00: Prof. Yurii Yagupolskii
• 17:00 - 17:30: Prof. Liam Ball
  "New Strategies for the Arylation of Weak Nucleophiles"

• 16:00 - 16:30: Dr. Dmytro Radchenko
• 16:30 - 17:00: Prof. Olexandr Isayev
• 17:00 - 17:30:   Dr. Christian Lemmen
  "A Brief History of Chemical Space"

• 15:00 - 15:30: Dr. David Barret
  "Targeting ‘Undruggable’ Targets: pioneering novel applications of heterobifunctional degraders"
• 15:30 - 16:00: Dr. Sergiy Tyukhtenko
  "Temporal Binding Continuum in hMGL: A multi-state conformational cascade for mechanism-driven drug discovery"
• 16:00 - 16:30: Prof. John Irwin
  "Free public databases and services for ligand discovery, pushed to the limit and beyond by Enamine"

"Pseudo natural products – Evolution of a chemical-biological principle with a view to real drug discovery"

• 11:00 - 11:30: Prof. Jens Carlsson
  "Accelerating Drug Discovery through Virtual Screening of Ultra-Large Chemical Libraries"
• 11:30 - 12:00: Prof. Nathaniel Martin
  "A potent next-generation glycopeptide antibiotic with best-in-class potential"
• 12:00 - 12:30: Dr. Ed Griffen
  "New Protease inhibitor antivirals - adventures with coronaviruses and flaviviruses”

• 11:00 - 11:30: Dr. Modest von Korf
  "Molecular Complexity Guided Navigation in Combinatorial Spaces"
• 11:30 - 12:00: Dr. Dragos Horvath
  "Reaction Condition Modelling: The Chemoinformatics of Kitchen Recipes"
• 12:00 - 12:30: Dr. Christoph Gorgulla
  "AI-enhanced adaptive virtual screening platform enabling exploration of 69 billion molecules discovers structurally validated FSP1 inhibitors"

• 11:00 - 11:30: Dr. Kai Rosen
• 11:30 - 12:00: Prof. Ihor Komarov
• 12:00 - 12:30: Prof. Mark Levin
  "Skeletal editing with reagents commercialized by Enamine"

Computational Approaches to Navigate Ever-Growing Chemical Spaces for Drug Discovery

Cyclopropenes : New Synthesis Methods and Conversion into Bicyclic Isosteres

• 16:00 - 16:30:  Dr. Marc Nicklaus
  "FreeRingSpace: Accessing unexplored parts of chemical space "
• 16:30 - 17:00: Dr. Luc Van Hijfte
  "My 4 decades in the Pharmaceutical Industry: Riding the Wave of Change"
• 17:00 - 17:30: flash talks

• 16:30 - 17:00: Prof. Dnytro Volochnyuk
• 17:00 - 17:30: flash talks

• 16:00 - 16:30: Dr. Olga Tarhanova
  "Gigascale Virtual Screening of Enamine xREAL Space Identifies CCK1R Positive Allosteric Modulators with Minimal Intrinsic Agonist Activity"
• 17:00 - 17:30: flash talks

"Protein degraders as chemical tools and drugs"

• 12:30 - 13:00: Prof. Hanoch Senderowitz